JWH-018 (1-pentyl-3-(1-naphthoyl)indole) is an analgesic An analgesic is any member of the group of drugs used to relieve pain (achieve analgesia). The word analgesic derives from Greek an- ("without") and algos ("pain"). Analgesic drugs act in various ways on the peripheral and central nervous systems; they include paracetamol (para-acetylaminophenol, also known in the US as chemical from the aminoalkylindole family, which acts as a cannabinoid Before the 1980s, it was often speculated that cannabinoids produced their physiological and behavioral effects via nonspecific interaction with cell membranes, instead of interacting with specific membrane-bound receptors. The discovery of the first cannabinoid receptors in the 1980s helped to resolve this debate. These receptors are common in agonist at both the CB1 and CB2 receptors, with some selectivity for CB2.[1][2][3] It produces effects in animals very similar to those of THC Tetrahydrocannabinol (THC), also known as delta-9-tetrahydrocannabinol (Δ9-THC), Δ1-THC (using an older chemical nomenclature), or dronabinol, is the main psychoactive substance found in the cannabis plant itself, but with a longer duration of action.
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