Selective serotonin reuptake inhibitors or serotonin-specific reuptake inhibitor (SSRIs) are a class of compounds typically used as antidepressants in the treatment of depression, anxiety disorders, and some personality disorders. They are also typically effective and used in treating premature ejaculation problems as well as some cases of insomnia.

SSRIs are believed to increase the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor. They have varying degrees of selectivity for the other monoamine transporters, with pure SSRIs having only weak affinity for the noradrenaline and dopamine transporter.

The first class of psychotropic drugs to be rationally designed, SSRIs are the most widely prescribed antidepressants in many countries. A 2010 meta-analysis indicated that:

"The magnitude of benefit of antidepressant medication compared with placebo ... may be minimal or nonexistent, on average, in patients with mild or moderate symptoms. For patients with very severe depression, the benefit of medications over placebo is substantial."

From Wikipedia under the GNU Free Documentation License
Wed Jul 21 16:33:49 2010

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Cocaine ssri ritalin the ADHD drug for children So cocaine as well as Ritalin block dopamine transporters for the re uptake process and SSRIs block the incomming serotonin transporters Though this is a very generalised explanation I

From Yahoo Image Search: "SSRI"
Sun Jul 11 12:39:05 2010

Exercise on SSRI's - Social Anxiety Forum
socialanxietysupport.com
Exercise on SSRI's - Social Anxiety Forum

alex999

hu, 24 Jun 2010 18:11:41 GM

Has anyone else noticed a positive effect from exercising on an . SSRI. ? By that I mean vigorous exercise of 30 minutes plus. I noticed that exercise.

Social Anxiety Disorder NEJM
nejm.org
Social Anxiety Disorder NEJM

Franklin R. Schneier, MD

hu, 07 Sep 2006 05:00:00 GM

Treatment with an . SSRI. or an SNRI is commonly initiated at half the usual effective dose, and the dose is increased after 1 week (Table 3). The dose response curve for these agents is relatively flat in social anxiety disorder,37 but ...

 SSRI Lawsuits Information | Reference & Education Articles
reference-education-articles.revisalo.info
SSRI Lawsuits Information | Reference & Education Articles

unknown

Sun, 25 Jul 2010 18:48:39 GM

While numerous . SSRI. lawsuits have been filed charging that the antidepressants​ caused patients to exhibit violent behavior, new information indicates that . SSRI. .

From Google Blog Search: "SSRI"
Tue Jul 27 08:44:38 2010

Best Evidence Interview: Use of Some SSRIs With Tamoxifen Increases Mortality ... - Medscape
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Best Evidence Interview: Use of Some SSRIs With Tamoxifen Increases Mortality ...

Medscape

[1-3] Among the drugs that inhibit CYP2D6 are the selective serotonin reuptake inhibitor ( SSRI ) antidepressants. It has been estimated that up to 25% of ...



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Grieving Nunavut mother seeks answers at inquest - Nunatsiaq News
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Grieving Nunavut mother seeks answers at inquest

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The Physicians Desk Reference states that SSRI antidepressants and all antidepressants can cause mania, psychosis, abnormal thinking, paranoia, hostility, ...



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From Google News Search: "SSRI"
Tue Apr 20 05:06:55 2010

How many beans do I need to take if I'm on prescribed SSRI?
Q. Okay, so I'm on 100mg prescribed SSRI (zoloft), and I want to take beans and actually feel the effects. I know that just one doesn't work, because I've tried that before and didn't feel a thing. So, my questions is, how many beans should I take to roll? Two? Give me your input, wise ones. And if you're just going to post with "drugs r bad", you can gtfo, I'm not here for that nonsense.
Asked by Olivia - Thu Nov 5 17:21:24 2009 - - 2 Answers - 1 Comments

A. No amount.. you can't roll while zoloft is in your system, sorry. You need to stop taking the zoloft (which I don't recommend, mind you) for, I'd say, 1.5 - 2 weeks before you try it. The SSRI's stop your serotonin from increasing, which is what makes you feel good when you roll. It keeps your serotonin at a constant amount, so now matter how much ecstasy you throw at it, it will only let a steady amount of serotonin in. So sorry, but it's one or the other. Maybe ask your doctor for a non-SSRI medication (be sure to have a reason), and 2 weeks later, you'll be set. Have fun, be safe.
Answered by unknown - Thu Nov 5 18:22:20 2009

What is the best SSRI (Antidepressant) MEDICATION FOR IF YOU WANT TO KILL YOURSELF?
Q. Is it Paxil or Zoloft? Or is it something completely different? Which made you feel the best?
Asked by Marx - Mon Nov 20 23:36:14 2006 - - 19 Answers - 0 Comments

A. They are both anti-depressants geared for different reasons. Paxil is more for social anxiety; people who consider themselves to be socially awkward are generally given paxil. Zoloft is more the general anti-depressant, with less specialized reasons for taking it. It is a hot topic right now. Before you do anything, get help! Psychiatrist can do wonders. Please, do this before you hurt yourself, please keep keep in mind that there are people out there who care about you and love you. Good luck
Answered by cutegirl - Mon Nov 20 23:52:20 2006

What is the roll of serotonin in sleep and how is this affected by SSRI's?
Q. Yea I've done x and it sure does keep you up but it also has stimulants such as MDMA and cocaine or meth mixed into the design of the drug. SSRI's are what I was actually wondering about. Thanks ravers.
Asked by burtongrl - Tue Nov 18 02:07:17 2008 - - 2 Answers - 0 Comments

A. more seratonin=less sleep. i know cause when i take ecstasy its releasing seratonin into my body and when im on it im crazy and cant sleep
Answered by yes - Tue Nov 18 02:15:10 2008

From Yahoo Answer Search: "SSRI"
Mon Nov 30 20:39:49 2009

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Sun Jul 25 12:36:36 2010